Sons Minoxidil 5% Cutaneous Solution, Hair Regrowth & Thickener Formula, For Hair Loss & Thinning in Men, Reactivates Shrunken Follicles, Precision Application System, 1 Month Supply

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Minoxidil is the most effective hair loss treatment for women and the second most effective hair loss treatment for men, after finasteride. Finasteride is a tablet taken every day to combat male pattern baldness, and is sometimes branded in the UK as Propecia. However it must not be taken by women. In one study, Propecia was shown to be effective at halting hair loss and promoting regrowth in 90% of men who used it. Learn more about Finasteride (Propecia) here. Scientists first developed minoxidil in the 1950s. Upjohn, the company that manufactured it, originally hoped to sell it for the treatment of ulcers but eventually marketed it as a vasodilator. If you want to use this 10% strength, you will only be able to do so through prescription. You will also need the oversight of a doctor for as long as you continue treatment.

As of June 2017 [update], Minoxidil was marketed under many trade names worldwide: Alomax, Alopek, Alopexy, Alorexyl, Alostil, Aloxid, Aloxidil, Anagen, Apo-Gain, Axelan, Belohair, Boots Hair Loss Treatment, Botafex, Capillus, Carexidil, Coverit, Da Fei Xin, Dilaine, Dinaxcinco, Dinaxil, Ebersedin, Eminox, Folcare, Follixil, Guayaten, Hair Grow, Hair-Treat, Hairgain, Hairgaine, Hairgrow, Hairway, Headway, Inoxi, Ivix, Keranique, Lacovin, Locemix, Loniten, Lonnoten, Lonolox, Lonoten, Loxon, M E Medic, Maev-Medic, Mandi, Manoxidil, Mantai, Men's Rogaine, Minodil, Minodril, Minostyl, Minovital, Minox, Minoxi, Minoxidil, Minoxidilum, Minoximen, Minoxiten, Minscalp, Mintop, Modil, Morr, Moxidil, Neo-Pruristam, Neocapil, Neoxidil, Nherea, Noxidil, Oxofenil, Pilfud, Pilogro, Pilomin, Piloxidil,Re-Stim, Re-Stim+, Recrea, Regain, Regaine, Regaxidil, Regro, Regroe, Regrou, Regrowth, Relive, Renobell Locion, Reten, Rexidil, Rogaine, Rogan, Si Bi Shen, Splendora, Superminox, Trefostil, Tricolocion, Tricoplus, Tricovivax, Tricoxane, Trugain, Tugain, Unipexil, Vaxdil, Vius, Women's Regaine, Xenogrow, Xtreme Boost, Xtreme Boost+, Xue Rui, Ylox, and Zeldilon. [60] It was also marketed as combination drug with amifampridine under the brand names Gainehair and Hair 4 U, and as a combination with tretinoin and clobetasol under the brand name Sistema GB. [60] Veterinary uses [ edit ] If the desired decrease of diastolic blood pressure exceeds 30 mmHg, dosage should be divided to two daily doses to keep daily blood pressure fluctuations as low as possible. DeClementi C, Bailey KL, Goldstein SC, Orser MS (November 2004). "Suspected toxicosis after topical administration of minoxidil in 2 cats". Journal of Veterinary Emergency and Critical Care. 14 (4): 287–292. doi: 10.1111/j.1476-4431.2004.04014.x.Dose-response is a common theme in scientific research. In simplest terms, it means that effectiveness increases as dosage increases, but only up to a certain point. After that point, further increases in dosage will produce no additional therapeutic benefit. They will only increase the side effects. Before starting treatment parents and carers should be warned of the likely occurrence of hypertrichosis.

Over time, scientists performed further studies to better understand minoxidil’s role in the treatment of hair loss. This eventually led to the FDA approving it against male pattern baldness in 1988. It has been available ever since. The method of application will differ depending on whether you are using lotion or foam, but the basic technique is to apply a small amount (usually 1ml) very carefully to areas of the scalp affected by balding and to massage it into the skin. If you are using liquid minoxidil, it is likely that you will be provided with an applicator to make the process easier and more accurate. don’t wash your hair, go swimming, or allow your hair to get wet in the rain for at least four hours after using Minoxidil The only head-to-head study comparing oral minoxidil to topical minoxidil in women with Female Pattern Hair Loss showed that 1mg of minoxidil gave comparable effects to 5% solution (1ml) once a day (Ramos et al. 2020). In this study, 26 women received oral minoxidil and 26 women received topical minoxidil. After 24 weeks of treatment, there was a 12% increase in hair density for women on oral minoxidil and 7.2% increase for women applying topical minoxidil. The difference was not statistically significant, but the oral minoxidil group also had less hair shedding. What are the side effects? Diuretic treatment alone, or in combination with restricted salt intake is, therefore, necessary for all patients taking minoxidil. Haemodilution may occur leading to temporary decrease in haematocrit, haemoglobin, and erythrocyte count (by approximately 7 % initially which then recovers to pre-treatment levels). The patient's bodyweight, fluid and electrolyte balance should be monitored for evidence of fluid retention.Conditions such as Cantú syndrome have been shown to mimic the pharmacological properties of minoxidil. [41] Chemistry [ edit ] There is limited data from the use of minoxidil in pregnant women. Studies in animals have shown reproductive toxicity (see section 5.3). Ramos, P. M., Sinclair, R. D., Kasprzak, M. & Miot, H. A. Minoxidil 1 mg oral versus minoxidil 5% topical solution for the treatment of female-pattern hair loss: A randomized clinical trial. J Am Acad Dermatol 2020; 82: 252–253

Pekmezci E, Türkoğlu M (December 2017). "Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line" (PDF). Acta Dermatovenerologica Croatica. 25 (4): 271–275. PMID 30064598. Statistically, even the 5% version of minoxidil will only work for around 1 out of every 2 men at best. The rest will see no results ( 6).

Minoxidil at 2% and 5% are barely absorbed systemically. However, as the strength increases, it is inevitable that at some point some of the minoxidil will be absorbed into circulation. At this point, side effects become very common and more severe. This is one of the reasons that strengths higher than 5% are not FDA-approved and are relatively difficult to find. a b Goldfarb NM (March 2006). "When Patents Became Interesting in Clinical Research" (PDF). The Journal of Clinical Research Best Practices. 2 (3). Archived from the original (PDF) on May 18, 2015 . Retrieved May 11, 2015. Before starting treatment, parents and carers should be warned of the likely occurrence of hypertrichosis.

Minoxidil topical foam or solution is for use on the scalp only. Keep this medicine away from the eyes, nose, and mouth. If you should accidentally get some in your eyes, nose, or mouth, flush the area thoroughly with cool tap water. If you are using the pump spray, be careful not to breathe in the spray . At least 90 % of the administered minoxidil is metabolized in the liver. The primary metabolite in humans is the minoxidil O-glucuronide. Some polar metabolites are also produced. The known metabolites have a weaker antihypertensive effect than the active ingredient itself.

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Immediately after using this medicine, wash your hands to remove any medicine that may be on them . drug allergy – NB it appears that oral minoxidil is safe if you have reacted to topical minoxidil even if your patch tests shows you react to minoxidil and not to the preservatives sun propylene glycol (Thearinou et al 2020)